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December 6, 2021

Nonmotor Seizures Delay Diagnosis of Focal Epilepsy Nonmotor Seizures Delay Diagnosis of Focal Epilepsy

Patients with focal nonmotor seizures experience a “disproportionate delay to diagnosis” compared with those with focal motor seizures, especially among teens, new research suggests. Retrospective analyses […]
December 3, 2021

Rituximab Trumps Natalizumab in MS Relapse Rituximab Trumps Natalizumab in MS Relapse

Rituximab (Rituxan) provides consistently better relapse outcomes than natalizumab (Tysabri) in patients with multiple sclerosis (MS), new research suggests. Findings from a real-world “comparative effectiveness study,” […]
December 3, 2021

Bedside Tool May Flag Brain Dysfunction in the Critically Ill Bedside Tool May Flag Brain Dysfunction in the Critically Ill

Key Takeaway A preliminary, unpublished study that used noninvasive diffuse correlation spectroscopy (DCS) to assess cerebral blood flow (CBF) in patients undergoing extracorporeal membrane oxygenation (ECMO) […]
December 1, 2021

More Evidence to Focus on Tau in Alzheimer’s Disease More Evidence to Focus on Tau in Alzheimer’s Disease

Key Takeaway A comprehensive reference map of metabolic brain changes in Alzheimer’s disease (AD) provides strong evidence of alterations in bioenergetic pathways, cholesterol metabolism, neuroinflammation, osmoregulation, […]
November 30, 2021

Microbleeds, Age Contribute to ARIA Risk With Aducanumab Microbleeds, Age Contribute to ARIA Risk With Aducanumab

Though primary efficacy results have yet to be published, new safety findings from two large, randomized trials of aducanumab offer details on which patients are more […]
November 24, 2021

Coffee, Smoking and Aspirin Influence Parkinson’s Disease Onset Coffee, Smoking and Aspirin Influence Parkinson’s Disease Onset

Coffee drinking, aspirin use, and smoking influence the age of onset and the extent of clinical symptoms in patients with Parkinson’s disease (PD), early research suggests. […]
November 22, 2021

Post-TBI Cognitive Changes ‘Strikingly’ Similar to Early Parkinson’s Post-TBI Cognitive Changes ‘Strikingly’ Similar to Early Parkinson’s

Veterans who have sustained a mild traumatic brain injury (mTBI) show signs of premature cognitive decline that are comparable to those in patients with early Parkinson’s […]
November 19, 2021

Erenumab Bests Topiramate in First Head-to-Head Migraine Trial Erenumab Bests Topiramate in First Head-to-Head Migraine Trial

Erenumab, a calcitonin-gene related peptide receptor (CGRP) inhibitor, is more tolerable and effective than topiramate for treating patients with migraine, according to data from almost 800 […]
November 19, 2021

Largest Review on Clinical Features of Daily Persistent Headache Largest Review on Clinical Features of Daily Persistent Headache

Most cases of new daily persistent headache (NDPH) are moderate to severe and many feature characteristics often associated with migraine, according to a new retrospective chart review. […]
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