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May 6, 2020

GI Symptoms in Parkinson’s Disease Correlate With Less Microbial Diversity GI Symptoms in Parkinson’s Disease Correlate With Less Microbial Diversity

Gastrointestinal symptoms are more common and severe in patients with Parkinson’s disease than in controls and may relate to an altered microbiome composition and reduced microbial […]
May 6, 2020

Serum NfL in Early MS Can Help Predict Clinical Course Serum NfL in Early MS Can Help Predict Clinical Course

The serum level of neurofilament light chain (sNfL) around the time of multiple sclerosis (MS) diagnosis is associated with long-term clinical disease progression, with higher baseline […]
May 5, 2020

Cautionary Findings on Immunodeficiency From Anti-CD20 MS Therapy Cautionary Findings on Immunodeficiency From Anti-CD20 MS Therapy

REPORTING FROM AAN 2020 Thirty-eight percent of a large cohort of multiple sclerosis (MS) patients developed low IgM and 7.4% became hypogammaglobulinemic during a mean 30 […]
May 5, 2020

New Angiotensin Studies in COVID-19 Give More Reassurance New Angiotensin Studies in COVID-19 Give More Reassurance

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Four more studies of the relationship of angiotensin-converting enzyme (ACE) inhibitors and […]
May 5, 2020

Botulinum Toxin Reduces Chronic Pelvic Pain in Endometriosis Botulinum Toxin Reduces Chronic Pelvic Pain in Endometriosis

Women with chronic pelvic pain (CPP) associated with endometriosis may benefit from an injection of botulinum toxin A (Botox, Allergan) without suffering significant adverse events, a […]
May 5, 2020

Economic Burden of Migraine Increases With Each Failed Treatment Economic Burden of Migraine Increases With Each Failed Treatment

From AAN 2020 Among patients with migraine, increase in the number of treatment failures is associated with increase in economic burden, researchers wrote. Utilization of health […]
May 5, 2020

Initial High-Efficacy MS Therapy Tied to Less Disability Later Initial High-Efficacy MS Therapy Tied to Less Disability Later

Starting treatment for relapsing-remitting multiple sclerosis (MS) with high-efficacy therapy (HET) is associated with lower long-term disability compared with a step-wise increase to reach more aggressive […]
May 4, 2020

Five-Year Siponimod Data Support Early MS Treatment Five-Year Siponimod Data Support Early MS Treatment

Among patients with secondary progressive multiple sclerosis (MS) who received siponimod or placebo during a double-blind trial and entered an open-label extension, those who received siponimod […]
May 4, 2020

Statins and ICH: New Meta-Analysis Statins and ICH: New Meta-Analysis

A new meta-analysis has concluded that the benefit of statin therapy in the prevention of ischemic stroke “greatly exceeds” the risk for intracerebral hemorrhage (ICH). The […]
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