TOPLINE: Pembrolizumab provided clinical benefit in previously treated advanced clear cell gynaecological cancer (CCGC). METHODOLOGY: A single-arm multicentre phase 2 trial conducted at five UK centres […]
TOPLINE: Among individuals using HIV pre-exposure prophylaxis (HIV PrEP), doxycycline post-exposure prophylaxis (doxyPEP) is associated with a substantial decline in chlamydia and syphilis incidence. METHODOLOGY: Researchers […]
TOPLINE: A 24-week phase 3 trial has found that once-daily vanzacaftor-tezacaftor-deutivacaftor is generally safe and well tolerated in children with cystic fibrosis aged 6-11 years. The […]
TOPLINE: Patients who experienced acute genitourinary and gastrointestinal toxicities following prostate cancer radiotherapy (RT) were more likely to have late toxicities and to experience declines in […]
TOPLINE: The use of rocuronium and sugammadex for reversing neuromuscular blockade increased dramatically over 6 years in patients with moderate and severe renal impairment. The variation […]
TOPLINE: Hospitalization for cannabis use disorder (CUD) is associated with a nearly threefold higher risk for premature death compared with the general population, with risk particularly […]
TOPLINE: Emergency department (ED) visits for previously undiagnosed pelvic organ prolapse (POP) revealed significant racial disparities in follow-up care, with non-Hispanic Black women experiencing the lowest […]
TOPLINE: Intermittent explosive disorder (IED) is associated with significantly higher odds of having psychiatric, neurologic, and somatic comorbidities, with 96% of patients having at least one […]
TOPLINE: According to a study of over five million patients with a neoplasm, those who received an immune checkpoint inhibitor (ICI) faced a 26% higher risk […]
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