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November 21, 2022

Sarilumab Effective for Polymyalgia Rheumatica in Phase 3 Trial Sarilumab Effective for Polymyalgia Rheumatica in Phase 3 Trial

PHILADELPHIA — Treatment with the interleukin-6 receptor antagonist sarilumab (Kevzara), along with a 14-week taper of glucocorticoids, proved to have significant efficacy in patients with relapsing […]
November 21, 2022

EMA Recommends Limiting the Indications for JAK Inhibitors EMA Recommends Limiting the Indications for JAK Inhibitors

AMSTERDAM — In an effort to minimize the risk of serious side effects associated with Janus kinase (JAK) inhibitors, the Pharmacovigilance Risk Assessment Committee (PRAC) of […]
November 18, 2022

Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden

PHILADELPHIA — Patients with gout who underwent an intensive treat-to-target regimen of monthly up-titration of urate-lowering therapy (ULT) to reach a target serum urate level were […]
November 18, 2022

First Classification Criteria Proposed for Chronic Osteomyelitis First Classification Criteria Proposed for Chronic Osteomyelitis

PHILADELPHIA — An international group of researchers has proposed the first classification criteria for chronic nonbacterial osteomyelitis (CNO) and a severe form of it, chronic recurrent […]
November 18, 2022

Opioids Increase Risk for All-Cause Deaths in RA vs. NSAIDs Opioids Increase Risk for All-Cause Deaths in RA vs. NSAIDs

PHILADELPHIA — For patients with rheumatoid arthritis who are already at increased risk for major adverse cardiovascular events (MACE), NSAIDs may be safer than opioids, results of […]
November 17, 2022

Combination Therapy May Boost Remission in JIA Combination Therapy May Boost Remission in JIA

PHILADELPHIA – Aggressive therapy using conventional synthetic disease-modifying antirheumatic drugs (DMARDs) in combination with biologic agents early, soon after a child is diagnosed with polyarticular juvenile […]
November 17, 2022

Education, Resetting Pain Expectations Vital to Less Opioid Use Education, Resetting Pain Expectations Vital to Less Opioid Use

Orthopedic surgeons are some of the biggest opioid medication prescribers — comprising the third highest in the United States. A webinar sponsored by the Hospital for […]
November 16, 2022

Combo Therapy Shows Mixed Results for SSc-Related Lung Disease Combo Therapy Shows Mixed Results for SSc-Related Lung Disease

PHILADELPHIA – Combining the immunomodulatory agent mycophenolate with the antifibrotic pirfenidone led to more rapid improvement and showed a trend to be more effective than mycophenolate […]
November 16, 2022

Prednisone, Colchicine Equally Efficacious for CPP Arthritis Prednisone, Colchicine Equally Efficacious for CPP Arthritis

PHILADELPHIA — Prednisone appears to have the edge over colchicine for control of pain in patients with acute calcium pyrophosphate (CPP) crystal arthritis, an intensely painful rheumatic […]
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