May 16, 2025
TOPLINE: Germinal center B-cell–like diffuse large B-cell lymphomas (GCB-DLBCLs) show dependence on DOT1L and EZH2, with combined targeting offering potential as an alternative differentiation-based therapy. DOT1L […]
May 16, 2025
Combination therapy with imlunestrant and the CDK4/6 inhibitor abemaciclib led to a significant progression-free survival (PFS) benefit compared with imlunestrant alone in women with estrogen receptor […]
May 15, 2025
The US Food and Drug Administration (FDA) has granted accelerated approval to telisotuzumab vedotin-tllv (Emrelis, AbbVie) for locally advanced or metastatic nonsquamous non–small cell lung cancer […]
May 15, 2025
The US Food and Drug Administration (FDA) has approved belzutifan (Welireg, Merck) for adult and pediatric patients aged 12 years or older with locally advanced, unresectable, […]
May 15, 2025
TOPLINE: Adding radium-223 dichloride (Ra223) to metastasis-directed stereotactic ablative radiotherapy (SABR) did not improve progression-free survival compared with SABR alone in men with bone-only oligometastatic castration-sensitive […]
May 15, 2025
TOPLINE: Remote symptom monitoring (RSM) using electronic patient-reported outcomes reduced hospitalizations by 19% at 3 months and 13% at 6 months in patients with cancer receiving […]
May 14, 2025
TOPLINE: In a multicenter cohort study of 575 South Korean patients with BRCA1 or BRCA2 pathogenic variants, breast-conserving treatment demonstrated comparable oncologic outcomes to mastectomy over […]
May 14, 2025
The trends are clear: Americans are in the midst of a marijuana high. Over the past 30 years, daily or near-daily marijuana use soared 15-fold, surpassing […]
May 14, 2025
TOPLINE: In patients with recurrent non–small cell lung cancer (NSCLC), salvage thoracic reirradiation prolonged overall survival and progression-free survival. Consolidative immunotherapy following reirradiation further improved overall […]