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June 5, 2022

Weekly Dulaglutide Promising in Youth With Type 2 Diabetes Weekly Dulaglutide Promising in Youth With Type 2 Diabetes

Another glucagon-like peptide-1 (GLP1) agonist, dulaglutide (Trulicity, Lilly), is poised to be a new option for glycemic control in youth ages 10 to 18 with type […]
June 5, 2022

‘Great Optimism’ Over Complete Responses in dMMR Rectal Cancer ‘Great Optimism’ Over Complete Responses in dMMR Rectal Cancer

Patients with locally advanced rectal cancer and tumors with deficient mismatch repair (dMMR) have shown a remarkable response to treatment with the programmed cell death-1 (PD-1) […]
June 4, 2022

Tirzepatide Powers ‘Unprecedented’ Weight Loss in SURMOUNT-1 Tirzepatide Powers ‘Unprecedented’ Weight Loss in SURMOUNT-1

Treatment of people with obesity but no diabetes with the dual incretin agonist tirzepatide safely produced “unprecedented” levels of weight loss in the vast majority of […]
June 4, 2022

Tirzepatide Powers ‘Unprecedented’ Weight Loss in Obesity Trial Tirzepatide Powers ‘Unprecedented’ Weight Loss in Obesity Trial

Dr Ania M. Jastreboff Treatment of people with obesity but no diabetes with the dual incretin agonist tirzepatide safely produced “unprecedented” levels of weight loss in […]
June 4, 2022

Bionic Pancreas: Closer to Fully Automated Insulin Delivery? Bionic Pancreas: Closer to Fully Automated Insulin Delivery?

The investigational insulin-only iLet Bionic Pancreas (Beta Bionics) reduced A1c without increasing hypoglycemia in adults and children with type 1 diabetes with greater automation than currently […]
June 4, 2022

ctDNA Identifies Colon Cancer Patients Who Can Skip Chemo ctDNA Identifies Colon Cancer Patients Who Can Skip Chemo

A “liquid biopsy” that detects circulating tumor DNA (ctDNA) after surgery for stage 2 colon cancer helps identify patients who are most likely to benefit from […]
June 4, 2022

Adagrasib Shows Durable Benefit in KRAS-Mutated NSCLC Adagrasib Shows Durable Benefit in KRAS-Mutated NSCLC

Adagrasib, an investigational drug that acts as a KRASG12C inhibitor, has shown durable clinical benefit in patients with previously treated, advanced non-small cell lung cancer (NSCLC) with tumors […]
June 4, 2022

Improved Survival in Subset of Advanced Pancreatic Cancer Improved Survival in Subset of Advanced Pancreatic Cancer

An investigational agent has shown promise in a subgroup of patients with advanced pancreatic cancer, offering hope of a clinical advance in a cancer that remains […]
June 4, 2022

‘Profound’ Results With Ibrutinib Add-On in Mantle Cell Lymphoma ‘Profound’ Results With Ibrutinib Add-On in Mantle Cell Lymphoma

Dr Michael Wang The largest trial to date in mantle cell lymphoma shows that adding the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib (Imbruvica) to standard of […]
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