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April 3, 2022

Diltiazem Fails to Improve Vasomotor Dysfunction, Angina in ANOCA Diltiazem Fails to Improve Vasomotor Dysfunction, Angina in ANOCA

In a randomized trial of patients with angina and no obstructive coronary artery disease (ANOCA), 6 weeks of treatment with diltiazem did not improve coronary vasomotor […]
April 3, 2022

Novel Cholesterol Drug Disappoints: TRANSLATE-TIMI 70 Novel Cholesterol Drug Disappoints: TRANSLATE-TIMI 70

An investigational drug targeting a novel cholesterol pathway has shown disappointing results in the TRANSLATE-TIMI 70 phase 2b study. Vupanorsen is an antisense oligonucleotide targeting hepatic […]
April 3, 2022

SCORED Trial: Sotagliflozin Showed Robust MACE Benefit SCORED Trial: Sotagliflozin Showed Robust MACE Benefit

WASHINGTON – Results from new analyses further fleshed out the potent effect by the investigational SGLT1&2 inhibitor sotagliflozin on major cardiovascular adverse events in patients with type […]
April 2, 2022

Hypertension Control During Pregnancy Validated in Large Trial Hypertension Control During Pregnancy Validated in Large Trial

Pregnant women with even mild hypertension should receive blood pressure–lowering medications to reduce the likelihood of adverse outcomes for the mother and the child, according to […]
April 2, 2022

VALOR-HCM: Novel Drug May Delay, Avert Invasive Therapy in OHCM VALOR-HCM: Novel Drug May Delay, Avert Invasive Therapy in OHCM

Treatment with a novel myosin-inhibiting agent may improve symptoms and hemodynamics enough in patients with obstructive hypertrophic cardiomyopathy (OHCM) so that they can avoid or at […]
April 2, 2022

POISE-3 Backs Wider Use of TXA in Noncardiac Surgery POISE-3 Backs Wider Use of TXA in Noncardiac Surgery

The antifibrinolytic tranexamic acid (TXA) reduced serious bleeding without a significant effect on major vascular outcomes in patients undergoing noncardiac surgery at risk for these complications […]
April 2, 2022

Low-Sodium Diet Did Not Cut Clinical Events in Heart Failure Low-Sodium Diet Did Not Cut Clinical Events in Heart Failure

A low-sodium diet was not associated with a reduction in future clinical events in a new study in ambulatory patients with heart failure. But there was […]
April 2, 2022

HIV PrEP: Biden Admin Allocates $9.8B for National Program HIV PrEP: Biden Admin Allocates $9.8B for National Program

For the past week, accolades and excitement have permeated the HIV advocacy space. The reaction is due to the March 28 release of the Biden Administration’s […]
April 1, 2022

CDC Recommends Hep B Vaccination for Most Adults CDC Recommends Hep B Vaccination for Most Adults

On March 31, the Centers for Disease Control and Prevention (CDC) recommended that all adults aged 19-59 years receive a vaccination for hepatitis B. It also […]
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