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May 22, 2023

Dupilumab Curbs Acute COPD Exacerbations Dupilumab Curbs Acute COPD Exacerbations

Dupilumab significantly reduced exacerbations in adults with chronic obstructive pulmonary disease by approximately 30% compared with placebo, based on data from approximately 900 individuals. Chronic obstructive […]
May 22, 2023

Machine Learning Model Improves MI Diagnosis Machine Learning Model Improves MI Diagnosis

Use of a machine learning model that incorporates information from a single troponin test as well as other clinical data was superior to current practice as […]
May 21, 2023

Tofacitinib De-escalation in UC: Proceed With Caution Tofacitinib De-escalation in UC: Proceed With Caution

A significant portion of patients with ulcerative colitis (UC) experience a flareup after dropping their tofacitinib (Xeljanz) dose from 10 mg twice a day to 5 […]
May 19, 2023

Transcatheter Tricuspid Valve Repair Effective in Real World Transcatheter Tricuspid Valve Repair Effective in Real World

Real-world data accumulated in Europe outside of a clinical trial support both the safety and the benefit of two transcatheter edge-to-edge (TEER) devices designed specifically for […]
May 19, 2023

COVID-Positive Donor Heart Tied to Lower Recipient Survival COVID-Positive Donor Heart Tied to Lower Recipient Survival

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A new study sounds a cautionary note about using donor hearts with […]
May 19, 2023

FDA Advisory Committee Votes Against Approval for NASH Drug FDA Advisory Committee Votes Against Approval for NASH Drug

The FDA Gastrointestinal Drugs Advisory Committee on Friday voted against the accelerated approval of Intercept Pharmaceutical’s obeticholic acid (OCA) for treatment of nonalcoholic steatohepatitis (NASH) with […]
May 19, 2023

Lupus Nephritis Treatment Response Biomarkers Gain Ground Lupus Nephritis Treatment Response Biomarkers Gain Ground

SEOUL, SOUTH KOREA – A panel of urinary biomarkers may do better than measuring proteinuria in predicting which patients with lupus nephritis are going to respond to […]
May 19, 2023

FDA Approves First-Ever Topical Gene Therapy FDA Approves First-Ever Topical Gene Therapy

The US Food and Drug Administration (FDA) has approved the first-ever topical gene therapy, which will be used to treat wounds in patients 6 months of […]
May 19, 2023

TNF, JAK Inhibitors’ CV Safety Compared in PsA, AxSpA TNF, JAK Inhibitors’ CV Safety Compared in PsA, AxSpA

CLEVELAND – Patients with axial spondyloarthritis or psoriatic arthritis who used Janus kinase (JAK) inhibitors did not have higher risk of myocardial infarction, stroke, or venous thromboembolism […]
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